Germany bound Germanwings plane crash lands in France with 148 people on board!

A Germanwings Airbus A320 plane carrying at least 148 people crashed Tuesday in the foothills of the Alps in southeastern France, French Prime Minister Manuel Valls told reporters.

Valls said he fears those aboard the flight from Barcelona, Spain, to Dusseldorf, Germany -- 142 passengers and six crew members -- may be dead.

French President Francois Hollande also said no survivors were expected. The plane crashed near Digne-les-Bains, in the Alpes de Haute Provence region, Valls said.

"The conditions of the accident are not yet clear but lead us to believe there will be no survivors," Hollande said.

A distress call associated with plane was sent at 10:45 a.m. local time (5:45 a.m. ET), French Interior Ministry spokesman Pierre-Henry Brandet told CNN affiliate BFMTV.

Germanwings Flight 9525 had left a Barcelona airport at 10:01 a.m., the airport website said.